In an analysis from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, one of the largest studies of its kind to determine whether intensive blood glucose (sugar) control worked better than standard blood sugar control among diabetics, results show that the benefits of intensive therapy need to be balanced against the increase in total and cardiovascular disease-related death, increased weight gain, and high risk for severe low blood sugar. The study is published by the Lancet to coincide with the American Diabetes Association’s 70th Scientific Sessions in Orlando. The analysis is written by Dr. Faramarz Ismail-Beigi, a diabetes specialist with University Hospitals Case Medical Center, Case Western Reserve University, and colleagues for the ACCORD trial group. ACCORD was a randomised trial done with more than 10,000 patients in 77 clinical sites, including University Hospitals Case Medical Center, in North America. People with Type 2 diabetes for an average of 10 years, high blood sugar concentrations and cardiovascular disease were randomly assigned to an intensive lowering of blood sugars or standard therapy.